The exact cause of gall bladder cancer is not known, but it is more likely to occur in people who have a history of gallstones, or in people who have benign (non-cancerous) tumours or polyps of the gall bladder. Gall bladder cancer is also slightly more common in people who are born with (congenital) abnormalities of the bile ducts, or people who have a condition called porcelain gall bladder, in which calcium forms in the wall of the gall bladder.

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